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Extrasynaptic GABAA receptors: their function in the CNS and implications for disease

Though there are a number of independent mechanisms implicated in the development of hypertension, sodium-dependent (high salt sensitivity) hypertension is linked to endothelial glycocalyx degradation (221)

If left unchecked, free radicals can cause oxidative stress, leading to inflammation, premature aging, and diseases like cancer

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Abd Elmageed Z, Yang Y, Thomas R, Ranjan M, Mondal D, Moroz K, et al

illustrated that PRL reduces the immune response to the effects of lipopolysaccharide (LPS)-induced inflammation by attenuating expression toll-like receptor 4 (TLR4) and nuclear factor kappa B cells (NF-B) with subsequent reduction release of pro-inflammatory cytokines, including TNF-, IL-1, and IL-6 [45]