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Read: Smoking Cessation Treatment Smokers Lungs After 30 Years Image source: After 30 years of smoking, the lungs will likely have irreversible damage and the risk of all types of disease is drastically increased, including lung cancer, COPD, and heart disease
The science isn't settled, but the direction is clear

Indeed, smokers tend to report elevated negative mood and a reduced ability to self-regulate such states when compared with nonsmokers [104, 105]

Many users find that their monthly vaping expenses are 50-70% lower than their previous smoking costs, even when choosing premium products

In the process, hed honor his own inspirationsBob Dylan, Harry Partch, Mose Allison, Captain Beefheartwhile inspiring countless younger artists who absorbed his profound influence on how great songs get made and sung