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The rats were given 5 days to recover from transportation before being subjected to surgeries, as described in this paragraph

22 Interestingly, the disruption to EC junctions seems to be repaired after paracellular extravasation, without significant damage to the BBB

10.1590/s0102-865020190070000008 129 WeiY.WuY.FengK.ZhaoY.TaoR.XuH.et al (2020)

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10.1111/febs.15669 55 HuX.CaiX.MaR.FuW.ZhangC.DuX

Histopathologically, PPA-treated rats exhibited hippocampal neurodegeneration, a crucial region for social and cognitive processing (Schwartzer et al., 2013