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Description
showed that the administration of agmatine in BDL rats for seven days after bile duct ligation was able to reduce ROS and nitric oxide formation and lipid peroxidation, and to increase mitochondrial GSH both in the liver and in the kidney in a dose-dependent way [200]
Guan et al
Additionally, it exhibits potential protective effects against HCC through the modulation of inflammatory, angiogenic, and oxidative stress pathways [231]
Second, the reagents and by-products formed should not be toxic or interfere with experimental biological studies
The caloric composition of the normal chow diet consisted of 23% protein, 21.6% fat, and 55.4% carbohydrates, while the HFD contained 20% protein, 60% fat, and 20% carbohydrates
Cip1/WAF1 Dimri GP et al
