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OHB signaling via GPR109A also regulates inflammation via NLRP3 (NOD-,LRR-and pyrin domain-containing protein 3) (Macia et al., 2015), reverse cholesterol transport (Wu and Zhao, 2009), atherosclerosis (Zhang et al., 2021) and neuroprotection (Rahman et al., 2014)

This process is vital for effective fat burning, especially during exercise or calorie-restricted diets, supporting both weight management and reduced fatigue

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found that RAGE knockout mice infected with S

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