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The comorbidity spectrum encompasses epilepsy, anxiety, sensory abnormalities, and other multisystem disorders, necessitating comprehensive strategies targeting GABA receptors, ion channel regulation, and the gut-brain axis ( 4.4 The application of GABAergic drugs in the treatment of ASD 4.4.1 GABA receptor agonists In the clinical treatment of ASD, the application of GABA receptor agonists is becoming increasingly widespread

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doi: 10.3126/janr.v4i2.33950 125 MaoH.WangH.LiuS.LiZ.YangX.YanJ.et al

*Correspondence: Ka Li, [email protected]

Considering Grx2s effects on proliferation and migration, proteins like actin, tubulin, and dihydropyrimidinase-related protein 2 (DPYL2) with key cysteine residues are regulated by Grx2c