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Changes in how the adenosine receptor functions due to genetic variants (see the genotype report below) can alter a persons response to caffeine, including whether coffee increases anxiety .[ref] Caffeine Metabolism: CYP1A2 CYP1A2 is a phase I detoxification enzyme that breaks down caffeine, as well as several other important toxins such as aflatoxin B1 from mold
Metabolomics studies small molecule metabolites, offering key clues for discovering cancer treatment targets (Schmidt et al., 2021)
