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For example, when hepatocytes are depleted of cholesterol, SCAP transports SREBP from the ER to the Golgi, where two proteases, Site-1 protease and Site-2 protease act in sequence to release the NH the ER to the Golgi, where two proteases, Site-1 protease and Site-2 protease act in sequence to release the NH 2 terminal of SREBP from the membrane (see also Fig

Additionally, the nitrogen atom in pyridine compounds provides extra hydrogen-bonding capacity, supporting interactions with analytes and facilitating the ionization reaction

J., Hoodless A., Muller K

Sep 15 2014;113(1-2):1-6