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SLIDESHOW See Slideshow Medically Reviewed on 6/2/2026 Frontiers in Bioscience Scholar: "Anti-atherosclerotic and cardiovascular protective benefits of Brazilian nuts." Harvard Medical School Harvard Health Publishing: "All about inflammation," "Nuts A healthy treat," "Quick-start guide to nuts and seeds." Pennsylvania State University Plant Village: "Brazil nut." Harvard T.H

PMID: 8 HuangS-FXuJ-LRenC-HSimNHanCHanY-Qet al

An in-depth study revealed that TPs significantly upregulated LC3-II/I and Beclin-1 expression and reduced SQSTM1/p62 expression in rat myocardial tissue (147)

Yet, amidst all the hype, some ingredients stand out due to their scientifically-backed benefits

In the next sections, we will briefly introduce thiazides, thiazide-like and loop diuretics from a historic perspective to illustrate how the success of one specific class of these diuretics in treating hypertension overshadowed their undesired metabolic effects and reduced our curiosity to study them to better understand their basic and clinical pharmacology

Park EJ, Kim YM, Kim HJ, Chang KC (2018) Luteolin activates ERK1/2- and Ca2+-dependent HO-1 induction that reduces LPS-induced HMGB1, iNOS/NO, and COX-2 expression in RAW264.7 cells and mitigates acute lung injury of endotoxin mice