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The activation of lipid synthesis pathways accelerates cancer cell proliferation, while lipid peroxidation in metabolic processes can increase oxidative stress, promoting cancer progression [269, 270]

Luo et al., 2022

Interference with gut ecological balance increases intestinal barrier permeability, allowing bacterial translocation

For example, circTRIM1 enhances MARCKS translocation and activates the PI3K/AKT/mTOR signaling pathway, promoting chemoresistance to doxorubicin in TNBC

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One enzyme, CSE, supports the biosynthesis of persulfides, primarily by generating H 2 S from Cys, but potentially also by generating cysteine persulfide from cystine 14
