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On day 22, a 24-hour urine sample was collected from each animal using a metabolism cage with a urine collection system for dogs and a specialized litter box for cats

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Drug/Laboratory Test InteractionsThe following drugs or moieties are known to interfere with laboratory tests performed in patients on thyroid hormone therapy: androgens, corticosteroids, estrogens, oral contraceptives containing estrogens, iodine-containing preparations, and the numerous preparations containing salicylates

doi: 10.3945/ajcn.111.012047

There were no major side effects that led to withdrawal from the clinical trial prior to the last assessment

It is particularly beneficial for overweight dogs, breeds prone to dilated cardiomyopathy (like Boxers and Dobermans), and senior dogs with reduced energy