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Description
Lower NAD+ also affects DNA methylation patterns

Oral supplementation almost never produces symptoms because the body absorbs only a small fraction of high-dose oral B12 and excretes the rest
Anywhere from 1-3 months
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Q., Zhu X

People who do not eat meat, fish, poultry, or dairy are at risk of becoming deficient in vitamin B12, since it is only found naturally in animal products
