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[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Carvalho A

Skin Brightening Inhibits melanin production by blocking the enzyme tyrosinase Helps reduce hyperpigmentation, sun damage, melasma, and uneven skin tone Promotes a clearer, more radiant complexion 2
It can bind to the IL-18 receptor (IL-18R), leading to the inhibition of transcription factors NF-B and MAPK

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Following the injection, in vivo imaging was conducted using an IVIS Spectrum (PerkinElmer) at various time points: 1 h, 2 h, 4 h, 6 h, 8 h, 12 h, 24 h, and 48 h post-injection, utilizing an excitation wavelength of 780 nm and a fluorescence emission wavelength of 840 nm
