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Boeuf S, Keijer J, Franssen-Van Hal NL, Klaus S
10.1016/j.tcb.2016.05.004 298 PrusinerS
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Repurposing of auranofin: Thioredoxin reductase remains a primary target of the drug
M.CromheekeK

The Gasotransmitter hydrogen sulfide induces Nrf2-target genes by inactivating the Keap1 ubiquitin ligase substrate adaptor through formation of a disulfide bond between Cys-226 and Cys-613