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The underlying mechanisms of these effects are diverse and appear to involve the regulation of various molecular targets, including transcription factors (such as nuclear factor-kB)[262] Resveratrol Resveratrol has been shown in the literature to have powerful anti-inflammatory effects which involve multiple pathways including inhibiting NF-kB, inhibiting iNOS (inducible-nitric oxide synthase) expression and inhibiting inflammatory cytokines such as IL-6 in various inflammatory conditions, including multiple sclerosis [263], diabetic neuropathy [264], arthritis [265], autoimmune myocarditis [266], colitis [267], and exerts immunomodulatory effects both in vitro and in vivo in lymphocytic leukemia

Like many vitamins in the B complex, it also acts as a coenzyme

The density of protein bands from the scanned images was analyzed using ImageJ ( Immunocytochemical analysis Immunofluorescent staining of cultured ONH astrocytes was performed as previously described