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From a clinical perspective, it suggests that in disease states with high IL-5 (like hypereosinophilic syndromes or active IBD with a type 2 skew), targeting Siglec-8 could be especially effective in depleting pathogenic eosinophils

Toxicology 439, 152466

A randomized, active-controlled, phase III clinical trial was performed in tuberculous meningitis (TBM) patients to assess the efficacity of aspirin to reduce mortality (ClinicalTrials.gov Identifier: NCT04145258)

[DOI] [PMC free article] [PubMed] [Google Scholar] 151.Liu X., Luo B., Wu X., Tang Z

Another problem of the KD is the inadequate amount of calcium [149]