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Funding The authors declare financial support was received for the publication of this article, which was covered by a grant from the Jeppe Juhl and wife Ovita Juhls Memorial Trust (to JF)

Research shows that increased KOR availability is linked to more severe anhedonia in people with schizophrenia, highlighting the link between this receptor system and challenges in reward processing and motivation [13]

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As an example, we used the common chemotherapeutic drug Doxorubicin, which can indeed induce senescence (Cahu et al., 2012