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Plant Physiol 131:656663 Lee SH, Ahsan N, Lee KW, Kim DH, Lee DG, Kwak SS, Lee BH (2007) Simultaneous overexpression of both CuZn superoxide dismutase and ascorbate peroxidase in transgenic tall fescue plants confers increased tolerance to a wide range of abiotic stresses

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E., Caldern-Oliver, M., Pedraza-Chaverri, J., & Chirino, Y

This additional step of dissociation is required because effective transduction across all cells within the 3D structure is not yet feasible, making it difficult to preserve the organoids spatial organization and cell-cell interactions