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Interestingly, finasteride also inhibits the activity of steroid 5-reductase, a soluble steroid reductase that belongs to the NADPH-dependent aldo-keto reductase (AKR) superfamily 43
Its interaction with the mutant SOD1 impairs its neuroprotective function and, along with the downregulation of VEGF, contributes to cytotoxicity and the appearance of neurodegenerative diseases like amyotrophic lateral sclerosis (159, 160)
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They have obtained something thats meant to be taken once a week, but theyre taking it every day because they thought it would work better, he said
Nature 386, 664
The cyclodextrin core solubilizes the hydrophobic Quercetin, while the CS-NAC coating provides mucoadhesion
