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In fact, the prenatal valproic acid exposure rodent model of ASD has been shown to manifest mitochondrial dysfunction (41)

When deficiencies exist, changing the diet may not be enough

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The present work was approved by the Internal Committee of Animal Welfare in Teaching and Research (Comit Interno de Bienestar Animal en la Enseanza e Investigacin, CIBAEI) and the Biosafety and Hygiene committee (Comit de Bioseguridad e Higiene, CBSH) of the School of Veterinary Medicine and Zootechnics of the Autonomous University of Nuevo Len, in addition to complying with the guidelines established in the Mexican norm NOM-062-ZOO-1999 (SENASICA)

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Databases searched (and their content coverage dates) were Ovid MEDLINE(R) (1946+ including epub ahead of print, in-process, and other nonindexed citations), Ovid Embase (1974+), Ovid APA PsycInfo (1967+), Ovid Cochrane Central Register of Controlled Trials (1991+), Ovid Cochrane Database of Systematic Reviews (2005+), Web of Science Core Collection via Clarivate Analytics (1975+), and Scopus via Elsevier (1974+)