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Moreover, increased phosphorylated p66Shc (p-p66Shc) interacts with peptidyl-prolyl cis/trans isomerase 1 (Pin1) to increase mitochondrial ROS and damage the retinal microvasculature in diabetic rats [106]

Acknowledgements A.S

J Biol Chem 285(47):36849

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For example, insulin tells your cells to absorb glucose
