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DRUG-FOOD INTERACTIONS AND ROLE OF PHARMACIST. Asian Journal of Pharmaceutical and Clinical Research , no

The gastro-resistant properties of the sucrosome shields the vitamin from premature release, degradation and minimizing interactions with food (27), as it passes through the stomach, ensuring that the B12 reaches the intestinal mucosa intact

This interaction is widely documented but frequently overlooked in clinical practice

Since then, it has been the subject of extensive scientific investigation

Preclinical Studies Early preclinical studies in rodent obesity models demonstrated that AOD9604 administration reduced body weight and fat mass without affecting food intake, indicating a direct metabolic effect rather than an appetite-suppressing mechanism
