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Melatonin synthesized in the pineal gland is rapidly and pulsatilely released into the bloodstream and cerebrospinal fluid, from where it is distributed to organs and tissues throughout the body. MELATONIN RECEPTORS Activation of melatonin receptors determines the subsequent biological effects

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Other functions of the circulatory system include hormone transport, protection against microorganisms, body thermoregulation, and control of pH levels in the body

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Methylcobalamin injections are the best form of B12