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Subsequently, several antibodies and tyrosine kinase inhibitors designed to target pro-angiogenic signaling have been approved as cancer therapies

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Icariin is a primary active constituent of Epimedium brevicomu , Epimedium sagittatum , Epimedium pubescens , and Epimedium koreanum

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Parisotto EB, Vidal V, Garca-Cerro S, Lantigua S, Wilhelm Filho D, Sanchez-Barcel EJ, Martnez-Cu C, Rueda N (2016) Chronic melatonin administration reduced oxidative damage and cellular senescence in the hippocampus of a mouse model of down syndrome