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Every cell releases an antioxidant enzyme which protects the cells during the metabolism of oxygen, and further breaks down the harmful free radicals into balanced molecules like water (Table 2)

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Interestingly, neutrophils of the horse lack defensins that depict mostly the main peptide type of these cells in other species

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NAD + is also involved in metabolic switching, or the Warburg effect, in which the main source of energy production is anaerobic glycolysis through fermentation of pyruvate to lactic acid, as opposed to mitochondrial oxidative phosphorylation 340