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The modulation of the vasomotor system involves ROS as mediators of vasoconstriction induced by angiotensin II, endothelin-1 and urotensin-II, among others

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In oxidative stress models, cells treated with GHK-Cu show 65% reduction in malondialdehyde levels (a lipid peroxidation marker) and 80% increase in total antioxidant capacity compared to controls