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Moreover, chronic IR in T2DM triggers adipose tissue inflammation, releasing pro-inflammatory cytokines (e.g., TNF- , IL-6) that impair hepatic insulin signaling and recruit circulating monocytes to the liver (9)

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Vitamin E treatment can also offer neuroprotective effects against excessive generation of ROS [176], suggesting anti-oxidative effects

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Shimura H, Schlossmacher MG, Hattori N, Frosch MP, Trockenbacher A, Schneider R, Mizuno Y, Kosik KS, Selkoe DJ (2001) Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinsons disease

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Perineuronal net degradation in epilepsy

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Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens

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