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Both enzymes, GPX7 and GPX8, are located in the endoplasmic reticulum and are necessary enzymes involved in the oxidative folding of endoplasmic reticulum proteins, and GPX8 also plays an important role in the regulation of Ca 2+ in the endoplasmic reticulum

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Abstract Astaxanthin, a lipid-soluble carotenoid, exhibits strong antioxidant activity in vitro and in animal studies, but its effectiveness in reducing exercise-induced oxidative stress in humans remains unclear due to inconsistent clinical findings