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Gong Y, Luo Y, Liu S, Ma J, Liu F, Fang Y, Cao F, Wang L, Pei Z, Ren J

the multifunctional growth factor hepatocyte growth factor (HGF) and its receptor Met are important mediators for mitogenesis, motogenesis, and morphogenesis in a wide range of cell types including epithelial, endothelial, and hematopoietic cells, neurons, melanocytes, and hepatocytes

NAD+ reduction increases methylation of certain gene promoters, which makes DNA methylation-sensitive factors detach and causes chromatin to compact and silence genes

Where evidence is anecdotal or practitioner-derived, it is labelled as such

While generally safe, common B12 side effects include diarrhea and swelling at the injection site

Heres the caveat: while the animal data is overwhelmingly positive, human studies are extremely limited