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Description
Phys Med Biol (1986) 31(2):12533
As a competitive inhibitor of xCT, it promotes GSH consumption while inhibiting the expression of the antioxidant H2S-producing enzyme cystathionine-synthase (CBS) to achieve oxidative stress toxicity
and Masood, Z
doi: 10.1002/jrsm.12 15
Knekt 1992
For example, PRMT1-mediated STAT6 methylation, induced by hypoxia-inducible factor (HIF)-1, promoted M2 macrophage polarization, contributing to fibrotic signaling in lung epithelial cells [91]
