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Collectively, our findings establish a novel link between the oncogene VRK2 and GSH synthesis metabolism, providing a molecular basis for developing stratified metabolic therapies for PC patients

10.1002/brb3.113 [DOI] [PMC free article] [PubMed] [Google Scholar] Nabah, Y

Transcriptomic analysis and qRT-PCR experiments revealed that their combination regulated AD-related pathways and genes more comprehensively, particularly affecting the Neuroactive ligand-receptor interaction and Calcium signaling pathway

These integrative and multidimensional interactions shape the system's behavior and must be considered comprehensively over time, space, and the context of appearance (177, 178)