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Here, we examined the effects of ARTHS mutations on histone acetylation in human cells and the effects of heterozygous loss of Kat6a in mice ( Kat6a +/ ) on learning, memory, activity, and sociability

Elevated TMAO downregulates hippocampal antioxidant enzyme MsrA, contributing to neuroinflammation and cognitive decline post-surgery in aged rats (143)

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In vivo, TMAO fell significantly in wild-type mouse models, and TMA levels fell significantly in FMO3-knockout (TMAU-model) mice

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