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Naringenin as a potential immunomodulator in therapeutics

Reduces oxidative stress and environmental skin damage

10.1016/j.smrv.2017.07.002 162 KovacevicA.FenesiB.PaolucciE.HeiszJ

In contrast, in ethanol-exposed Grx1 -deficient mice, accumulation of FAS-SSG drives hepatocyte apoptosis through dysregulation of NF-B and AKT serine/threonine kinase 1 (AKT1) signaling 47

doi: 10.2337/dc18-2182

Currently, a limited number of iron chelators have received approval from the FDA or are undergoing clinical trials for conditions such as iron overload-related diseases, organ damage, and transplants (Ballas et al., 2018)
