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doi: 10.1053/j.gastro.2020.10.066 165 MartinC

Intestinal dysbiosis and hormonal neuroendocrine secretion in the fibromyalgic patient

Oct 17 2021;11(10):1102
In simplified terms: BPC-157 Enhanced VEGFR2 signalling PI3K activation Akt activation eNOS phosphorylation Increased NO production This increased nitric oxide production leads to: Relaxation of vascular smooth muscle Arterial dilation Increased tissue perfusion Why This Matters Improved blood flow means: More oxygen delivery More nutrient transport Faster waste removal Better inflammatory resolution In injury models, increased perfusion strongly correlates with improved healing rates

The body uses vitamin C as an antioxidant, and it also plays a role in collagen production, which helps support skin structure

In recent years, GABA and glutamate have gained interest for their respective roles in the regulation of secretion of insulin and glucagon
