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Vickery BH, Avnur Z, Cheng Y, Chiou SS, Leaffer D, Caulfield JP, et al
FXR activation in macrophages may also indirectly reduce Th1 responses, as shown in models where FXR agonism diminished inflammation and IFN- + T cell populations (81)
doi: 10.1006/faat.1995.1100
In this context, Marklund et al
Phylum-level analyses indicate predominant Firmicutes with relative Bacteroidetes reduction in some studies (264, 265), while others report increased Actinobacteria , Verrucomicrobia , or pro-inflammatory Proteobacteria , alongside potential reduction of beneficial Bacteroidetes and Actinobacteria ( 262, 266)
Clinical and immunological parameters of Sjgrens syndrome
