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Using the prize-collecting Steiner tree algorithm, it searches the PPMI interactome to find an optimum subnetwork that connects the input metabolite peaks via their putative identities and other metabolites and proteins that were not detected in the experiments

doi: 10.1038/nature09819 264 WatanabeM.HoutenS

TGF-3Transforming growth factor-3

13 Being responsible for serum IL-1 and IL-18 levels elevation, this study confirmed that l-carnitine markedly downregulated renal rOCTN-2 protein levels to promote elimination efficiency of l-carnitine in both female and male rats, which were consistent with renal lipid depletion as well as TG, TC and VLDL level reduction