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Am J Respir Crit Care Med 167 : 395399 Reddy NM, Suryanarayana V, Kalvakolanu DV, Yamamoto M, Kensler TW, Hassoun PM, Kleeberger SR, Reddy SP 2009 Innate immunity against bacterial infection following hyperoxia exposure is impaired in nrf2-deficient mice

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Naturally present in the body, this peptide plays a vital role in maintaining healthy, youthful skinbut its levels decline with age, leading to visible signs like wrinkles, sagging, and uneven tone

Gene expression: GHK-Cu has been documented to up- or downregulate over 4,000 human genes in cell-culture models, affecting pathways related to inflammation, tissue repair, and antioxidant defense (PMID 29986520)

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