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Wong D, Schranz A, Bartha R

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Biochemical studies showed that ISCU expression was indeed markedly diminished in patient skeletal muscle samples, and DNA sequencing revealed that the myopathy allele contains a single G to C mutation near the middle of the final ISCU intron

This increased vascular normalization by bevacizumab allowed for enhanced delivery of the Hoechst dye in rabbit granulomas (58)

Preclinical studies, particularly in mouse models bearing CD38 + tumors, demonstrated preferential accumulation of the [ 64 Cu]Cu-DOTA-daratumumab within bone-associated tumor sites