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A distinguishing feature of TB-500 is its anti-fibrotic activity

Available as a lyophilized powder in 10 mg vials, it is administered via daily subcutaneous injection

5-Amino-1MQ is a small molecule compound and selective inhibitor of nicotinamide N-methyltransferase (NNMT)

Y-position cysteine substitution in type I collagen (alpha1(I) R888C/p.R1066C) is associated with osteogenesis imperfecta/EhlersDanlos syndrome phenotype

Furthermore, it promotes aggregation of RIPK1 that subsequently undergoes degradation via aggrephagy, further diminishing necroptotic activity (53)

Athletes should verify annually as the list is updated