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Rules of Good Laboratory Practice, approved by order of the Ministry of Health of the Russian Federation No

In phase I metabolism, GSTs catalyse the nucleophilic attack of the thiol group of reduced glutathione located in the electrophilic centre of lipophilic compounds, including OPs and pyrethroids, causing increased water solubility and excretion by the cells [118, 122, 123]

In a study, the gene expression of AMP (adenosine monophosphate)-activated protein kinase (AMPK), which regulates energy homeostasis, was modulated by apigenin

Constitutive and -naphthoflavone-induced expression of the human -glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence

doi: 10.1016/j.toxlet.2016.11.006

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