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These results were consistent with the results of a recent clinical trial on the efficacy of silymarin cream in comparison to HQ 4% cream for melasma management which reported significant ADRs in HQ group 53

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Tierney AC, Rumble CE, Billings LM, George ES (2020) Effect of dietary and supplemental lycopene on cardiovascular risk factors: a systematic review and meta-analysis

Both of these mutants fail to form spherules and although mice can be infected, the infection resolves spontaneously

Similarly, a defensive role against oxidative stress by RpGSTO1 towards different concentrations of CHP was observed in the bird cherry-oat aphid, Rhopalosiphum padi [131]