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This research was funded by Instituto de Salud Carlos III (PI23/00815) (co-funded by European Regional Development Fund A way to make Europe)

502 TORKIs have shown superior ability to sensitize cancer cells to DNA-damaging agents by disrupting DNA damage response pathways and interfering with cell cycle checkpoint control, a capability that rapalogs notably lacking
The sequestration of fibers in a non-reactive core is an important defense mechanism as the valence sites of ferric moieties are not available for electron exchange and generation of ROS
