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Chen J, Regan RF (2004) Heme oxygenase-2 gene deletion increases astrocyte vulnerability to hemin

A reliable biomarker of PA is elevated propionate levels in both blood and urine, as observed in PA patients and mouse models, although propionate is often underreported due to the need for advanced analytical techniques ( Our recent work demonstrated that ACSS3 activity in the liver is attenuated in Pcca / (A138T) mice ( If propionyl-CoA hydrolysis were highly efficient, the accumulation of propionyl-CoA might not take place the primary issue, and the elevated propionate or other metabolites could instead be the main disease-causing factor

doi: 10.1136/jcp.54.8.631

In Mineral Containing Proteins: Roles in Nutrition (ed

As a result, a link has been found between rs2631365-TC within the promoter region of OCTN2 and failure of imatinib treatment [71], highlighting the development of personalized therapy

Furthermore, ETC deficiencies are noted in the subunits that are encoded by the mitochondrial DNA, specifically in the ETC Complex III (Poling et al., 2006)