glutathione biosynthesis Figure 2 from Regulation of neuronal synthesis Glutathione synthesis and recycling. Glutathione

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All other data generated in this study are provided in the Supplementary Information/Source Data file

In a type 1 diabetic Akita mouse model, which was used as a nonobese insulin-dependent model of spontaneous type 1 diabetes, empagliflozin treatment attenuated diabetes-induced rise in renal expression of markers of kidney growth by reducing the cyclin-dependent kinase inhibitors p27 and p21, which were over-expressed in early diabetic kidneys (152)

Briefly, 1106 cells were incubated overnight in 100-mm dishes containing 10 ml of RPMI-1640 medium supplemented with 10% FBS without penicillin, streptomycin and neomycin