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The peptide, humanin, was ultimately traced to a tiny snippet of mitochondrial DNApart of the ninety-eight per cent of the human genome that had long been dismissed as junk DNA. Cohens work helped reveal that, in the three-billion-letter book that is our genome, even obscure one-liners can be an important part of the story

This suggests the peptide may influence cellular metabolism and tissue repair through multiple signaling pathways that remain incompletely characterized

By contrast, the SFSV effector protein NSs hijacks the eIF2-P binding pocket between eIF2B and eIF2B 69,70 but stabilizes an eIF2B A-state, suggesting a conformation complicit with latch-helix ordering

Food Chem 135:22382244

Glutathione reduces pigmentation and promotes an even skin tone

doi: 10.1126/science.1198904 122 SiemensJ.KammG