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Discovery of a novel NAMPT inhibitor that selectively targets NAPRT-deficient EMT-subtype cancer cells and alleviates chemotherapy-induced peripheral neuropathy

Lo A, Li CP, Buza EL, Blomberg R, Govindaraju P, Avery D, et al

Stress : The impact of stress on the gastrointestinal system is multifaceted, involving alterations in gut motility, microbial composition, and barrier function

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Weight loss begins but may be modest, averaging 2-4 pounds depending on starting weight and dose

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