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Conclusions This updated operational definition is the first to be informed by systematic methods, and could support the harmonization of CAIM-related research through the provision of a standard of classification, as well as support improved collaboration between different research groups

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While acanthosis nigricans is most often found in those who are obese, it also occurs with various endocrinopathies, malignancies, the metabolic syndrome, and the use of some medications

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Solar lentigines (liver spots, to many patients) are flat or almost flat brown marks most common on the backs of the hands, forearms and the face