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Phase II and Phase III are carried out by a much more generalized group of transferase and peptidase enzymes which do not exhibit the same degree of specificity as CYP450 enzymes.2 Being an enzymatic process, drug metabolism as a whole is highly susceptible to competition, inhibition, and induction
doi: 10.1038/nrendo.2016.53 2 OgurtsovaKda Rocha FernandesJDHuangYLinnenkampUGuariguataLChoNHet al
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3.5, 95% CI, 2.0, 4.9%
