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This type of stool is called melena and can be a sign of bleeding in the upper digestive tract, such as the esophagus, stomach, or small intestine

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As a heat-clearing drug in TCM, it is empirically applied in treating amenorrhea caused by blood-heat, infectious skin diseases, appendicitis, and wind-heat type rheumatic arthralgia

It may also be important in immune surveillance against cancer

Evolution and evaluation of autologous mini punch grafting in vitiligo