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Bakan et al., 2002)

postulated the role of indoxyl sulfate in the pathogenesis of renal anemia: indoxyl sulfate could stimulate oxidative stress and induce eryptosis through Organic Anion Transporter 2 (OAT2)- and NADPH oxidase-dependent, as well as GSH-independent mechanisms [257]

doi: 10.1148/rycan.240312

It can be used in many types of formulations as it has great thermal stability (can be heated up to 85C) and works on a wide range of pH levels (ph 3-10)

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